Novavax vaccine contains 1 mcg of insect and baculovirus proteins and a bit of their DNA

There is nothing “conventional” about the Novavax injections. Dr. Nass notes, “This vaccine is another ‘bait and switch’ being rolled out solely to entice the unvaccinated, because it is not made of mRNA.” Novavax hopes to do an end-run around mRNA vaccine fears and offer something more retro. Don’t be fooled. ⁃ Technocracy News Editor Patrick Wood

You see, the vaccine’s spike protein is grown by genetically engineering baculoviruses to produce spike, and then infecting insect cells with the baculovirus to turn the whole thing into a spike protein factory.

At the CDC’s Advisory Committee on Immunization Practices meeting that I live-blogged last week, it was revealed that the Novavax vaccine was being rolled out because it could be marketed as a “more traditional” vaccine, since it was not made from mRNA. Novavax was to be directed to the unvaccinated, although only 10% of the unvaccinated, it was anticipated, would accept it.

The fact that no fetal cells were used in its development was claimed to be a marketing plus. However, thanks to a reader, it turns out that a human fetal cell line, (HEK) 293F, was used in the testing of the vaccine, as described in an article in Science.

NOTHING about this vaccine is traditional.

First, the Novavax company does not own a manufacturing plant, so the vaccine being distributed in the US is made at the Serum Institute of India.

Second, the adjuvant, Matrix-M (a nonspecific, potent immune stimulant) has never been used before. It is made from the Quillaja saponaria tree. There is another adjuvant that is only used in one (highly reactogenic) US vaccine, Shingrix, which is an extract from this tree. This GSK adjuvant, named ASO1B, contains QS-21, a single extract in the Shingrix vaccine.

The problem is that we don’t know what extracts from the tree are included in Matrix-M. The information is proprietary! The Matrix-M adjuvant uses two unspecified “fractions” from the Q. saponaria tree, and there exist no data on its safety. (Matrix-M does not contain QS-21, although the company sometimes implies it does, to distract from its novelty.) These two fractions, combined with phospholipids and cholesterol, form the 40 nanometer particles of Matrix M.