top of page

"CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis"

You don't say...

Jessica Rose

Please refer to my previous article entitled: “Is SARS-nCoV-2-associated systemic micro-clotting due to spike protein-induced hemolysis resulting in amyloid plaque formation?”.

Then refer to a new publication entitled: “CD147 contributes to SARS-CoV-2-induced pulmonary fibrosispublished on November 25, 2022 in Nature Signal Transduction and Targeted Therapy. This is a published article which means it’s been peer-reviewed.

In this work, the authors exemplified our dear model mouse friends again. In their model, the mice were ‘humanized’; having been granted the human versions of CD147 (hCD147), thus making them susceptible to cell infection via CD147/spike protein binding by SARS-CoV-2, complete with symptoms! Or if you prefer: “SARS-CoV-2- and its delta variant-infected humanized CD147 transgenic mice”.

Here’s their conclusion:

In conclusion, we demonstrated that CD147 contributed to SARS-CoV-2-triggered progressive pulmonary fibrosis and identified CD147 as a potential therapeutic target for treating patients with post-COVID-19 pulmonary fibrosis.

As most of you know by now, in severe cases of COVID-19, for reasons as yet to be meticulously defined, severe lung pathologies can develop including pulmonary fibrosis. Pulmonary (lung) fibrosis (development of connective tissue as a repair function due to injury - which is normal) is very serious for the same reason myocardial scarring (or any pathological tissue scarring for that matter) is very serious. Inevitably, prevention of normal functioning of the tissue/organ - due to the replacement of normal cells or tissues with scar tissue - ensues.

Imagine if you replaced the rubbery surface of a balloon with sections or grafts of inflexible cardboard and then tried to blow up the balloon. It would pop because the paper is not flexible. Connective tissue formation is absolutely normal - essential, in fact - to our normal functioning. I mean, what would we do if we didn’t have connective tissue? We would simply fall apart! Like the narrative is doing!


bottom of page